Modeling the impact of drug interactions on therapeutic selectivity

Combination therapies that produce synergistic growth inhibition are widely sought after for the pharmacotherapy of many pathological conditions. Therapeutic selectivity, however, depends on the difference between potency on disease-causing cells and potency on non-target cell types that cause toxic...

Descripción completa

Detalles Bibliográficos
Autores principales: Weinstein, Zohar B., Kuru, Nurdan, Kiriakov, Szilvia, Palmer, Adam C., Khalil, Ahmad S., Clemons, Paul A., Zaman, Muhammad H., Roth, Frederick P., Cokol, Murat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110842/
https://www.ncbi.nlm.nih.gov/pubmed/30150706
http://dx.doi.org/10.1038/s41467-018-05954-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110842/
https://www.ncbi.nlm.nih.gov/pubmed/30150706
http://dx.doi.org/10.1038/s41467-018-05954-3

Ejemplares similares