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Importance of GPCR-Mediated Microglial Activation in Alzheimer’s Disease
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder associated with impairment of cognition, memory deficits and behavioral abnormalities. Accumulation of amyloid beta (Aβ) is a characteristic hallmark of AD. Microglia express several GPCRs, which, upon activation by modulators, med...
Autores principales: | Haque, Md. Ezazul, Kim, In-Su, Jakaria, Md., Akther, Mahbuba, Choi, Dong-Kug |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110855/ https://www.ncbi.nlm.nih.gov/pubmed/30186116 http://dx.doi.org/10.3389/fncel.2018.00258 |
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