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Metabolic Reprogramming of Clostridioides difficile During the Stationary Phase With the Induction of Toxin Production

The obligate anaerobe, spore forming bacterium Clostridioides difficile (formerly Clostridium difficile) causes nosocomial and community acquired diarrhea often associated with antibiotic therapy. Major virulence factors of the bacterium are the two large clostridial toxins TcdA and TcdB. The produc...

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Detalles Bibliográficos
Autores principales: Hofmann, Julia D., Otto, Andreas, Berges, Mareike, Biedendieck, Rebekka, Michel, Annika-Marisa, Becher, Dörte, Jahn, Dieter, Neumann-Schaal, Meina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110889/
https://www.ncbi.nlm.nih.gov/pubmed/30186274
http://dx.doi.org/10.3389/fmicb.2018.01970