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Oxygen Limitation Enhances the Antimicrobial Activity of Fosfomycin in Pseudomonas aeruginosa Following Overexpression of glpT Which Encodes Glycerol-3-Phosphate/Fosfomycin Symporter

Fosfomycin is resurfacing as a “last resort drug” to treat infections caused by multidrug resistant pathogens. This drug has a remarkable benefit in that its activity increases under oxygen-limited conditions unlike other commonly used antimicrobials such as β-lactams, fluoroquinolones and aminoglyc...

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Detalles Bibliográficos
Autores principales: Hirakawa, Hidetada, Kurabayashi, Kumiko, Tanimoto, Koichi, Tomita, Haruyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110920/
https://www.ncbi.nlm.nih.gov/pubmed/30186264
http://dx.doi.org/10.3389/fmicb.2018.01950