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Impaired Glycine Receptor Trafficking in Neurological Diseases

Ionotropic glycine receptors (GlyRs) enable fast synaptic neurotransmission in the adult spinal cord and brainstem. The inhibitory GlyR is a transmembrane glycine-gated chloride channel. The immature GlyR protein undergoes various processing steps, e.g., folding, assembly, and maturation while trave...

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Detalles Bibliográficos
Autores principales: Schaefer, Natascha, Roemer, Vera, Janzen, Dieter, Villmann, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110938/
https://www.ncbi.nlm.nih.gov/pubmed/30186111
http://dx.doi.org/10.3389/fnmol.2018.00291