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Investigating the relationship between DNA methylation age acceleration and risk factors for Alzheimer's disease
INTRODUCTION: The “epigenetic clock” is a DNA methylation–based estimate of biological age and is correlated with chronological age—the greatest risk factor for Alzheimer's disease (AD). Genetic and environmental risk factors exist for AD, several of which are potentially modifiable. In this st...
Autores principales: | McCartney, Daniel L., Stevenson, Anna J., Walker, Rosie M., Gibson, Jude, Morris, Stewart W., Campbell, Archie, Murray, Alison D., Whalley, Heather C., Porteous, David J., McIntosh, Andrew M., Evans, Kathryn L., Deary, Ian J., Marioni, Riccardo E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111045/ https://www.ncbi.nlm.nih.gov/pubmed/30167451 http://dx.doi.org/10.1016/j.dadm.2018.05.006 |
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