Generation of HIV-Resistant Macrophages from IPSCs by Using Transcriptional Gene Silencing and Promoter-Targeted RNA

Highly active antiretroviral therapy (HAART) has markedly prolonged the prognosis of HIV-1 patients. However, lifelong dependency on HAART is a continuing challenge, and an effective therapeutic is much desired. Recently, introduction of short hairpin RNA (shRNA) targeting the HIV-1 promoter was fou...

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Detalles Bibliográficos
Autores principales: Higaki, Kei, Hirao, Masako, Kawana-Tachikawa, Ai, Iriguchi, Shoichi, Kumagai, Ayako, Ueda, Norihiro, Bo, Wang, Kamibayashi, Sanae, Watanabe, Akira, Nakauchi, Hiromitsu, Suzuki, Kazuo, Kaneko, Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111070/
https://www.ncbi.nlm.nih.gov/pubmed/30141412
http://dx.doi.org/10.1016/j.omtn.2018.07.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111070/
https://www.ncbi.nlm.nih.gov/pubmed/30141412
http://dx.doi.org/10.1016/j.omtn.2018.07.017

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