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PAK1 Promotes the Proliferation and Inhibits Apoptosis of Human Spermatogonial Stem Cells via PDK1/KDR/ZNF367 and ERK1/2 and AKT Pathways

Spermatogonial stem cells (SSCs) have significant applications in reproductive and regenerative medicine. However, nothing is known about genes in mediating human SSCs. Here we have explored for the first time the function and mechanism of P21-activated kinase 1 (PAK1) in regulating the proliferatio...

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Detalles Bibliográficos
Autores principales: Fu, Hongyong, Zhang, Wenhui, Yuan, Qingqing, Niu, Minghui, Zhou, Fan, Qiu, Qianqian, Mao, Guoping, Wang, Hong, Wen, Liping, Sun, Min, Li, Zheng, He, Zuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111072/
https://www.ncbi.nlm.nih.gov/pubmed/30141410
http://dx.doi.org/10.1016/j.omtn.2018.06.006

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