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Simvastatin enhances irinotecan-induced apoptosis in prostate cancer via inhibition of MCL-1

Prostate cancer is one of the most common malignant tumors around the world. Hyperlipidemia is considered as one of the most important risk factors for the development of prostate cancer. Simvastatin is widely used for the treatment of hyperlipidemia and was previously shown to induce apoptosis in s...

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Detalles Bibliográficos
Autores principales: Alqudah, Mohammad A.Y., Mansour, Hebah T., Mhaidat, Nizar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111232/
https://www.ncbi.nlm.nih.gov/pubmed/30166915
http://dx.doi.org/10.1016/j.jsps.2017.12.012