Preparation and activity of glycosylated acetylsalicylic acid

The glycosylated acetylsalicylic acid was prepared with bromo-α-d-galactose and acetylsalicylic acid. It indicated that the glycosylated acetylsalicylic acid had lower cytotoxicity than underivatized acetylsalicylic acid, and might selectively display anticancer activity in this situation that had e...

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Detalles Bibliográficos
Autores principales: Huang, Gangliang, Cheng, Hao, Liu, Yang, Hu, Jinchuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111454/
https://www.ncbi.nlm.nih.gov/pubmed/30166926
http://dx.doi.org/10.1016/j.jsps.2017.12.001
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author Huang, Gangliang
Cheng, Hao
Liu, Yang
Hu, Jinchuan
author_facet Huang, Gangliang
Cheng, Hao
Liu, Yang
Hu, Jinchuan
author_sort Huang, Gangliang
collection PubMed
description The glycosylated acetylsalicylic acid was prepared with bromo-α-d-galactose and acetylsalicylic acid. It indicated that the glycosylated acetylsalicylic acid had lower cytotoxicity than underivatized acetylsalicylic acid, and might selectively display anticancer activity in this situation that had enzyme or no enzyme.
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spelling pubmed-61114542018-08-30 Preparation and activity of glycosylated acetylsalicylic acid Huang, Gangliang Cheng, Hao Liu, Yang Hu, Jinchuan Saudi Pharm J Original Article The glycosylated acetylsalicylic acid was prepared with bromo-α-d-galactose and acetylsalicylic acid. It indicated that the glycosylated acetylsalicylic acid had lower cytotoxicity than underivatized acetylsalicylic acid, and might selectively display anticancer activity in this situation that had enzyme or no enzyme. Elsevier 2018-02 2017-12-05 /pmc/articles/PMC6111454/ /pubmed/30166926 http://dx.doi.org/10.1016/j.jsps.2017.12.001 Text en © 2017 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Huang, Gangliang
Cheng, Hao
Liu, Yang
Hu, Jinchuan
Preparation and activity of glycosylated acetylsalicylic acid
title Preparation and activity of glycosylated acetylsalicylic acid
title_full Preparation and activity of glycosylated acetylsalicylic acid
title_fullStr Preparation and activity of glycosylated acetylsalicylic acid
title_full_unstemmed Preparation and activity of glycosylated acetylsalicylic acid
title_short Preparation and activity of glycosylated acetylsalicylic acid
title_sort preparation and activity of glycosylated acetylsalicylic acid
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111454/
https://www.ncbi.nlm.nih.gov/pubmed/30166926
http://dx.doi.org/10.1016/j.jsps.2017.12.001
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AT liuyang preparationandactivityofglycosylatedacetylsalicylicacid
AT hujinchuan preparationandactivityofglycosylatedacetylsalicylicacid

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