Cardiac arrest after ibogaine intoxication

Ibogaine is a psychoactive herbal medication with alleged antiaddiction properties. We report a case of ibogaine intoxication mimicking Long‐QT syndrome resulting in ventricular flutter and nearby cardiac arrest. A 61‐year‐old man experienced massive QT prolongation and ventricular flutter at a rate...

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Detalles Bibliográficos
Autores principales: Steinberg, Christian, Deyell, Marc W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111465/
https://www.ncbi.nlm.nih.gov/pubmed/30167018
http://dx.doi.org/10.1002/joa3.12061
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author Steinberg, Christian
Deyell, Marc W.
author_facet Steinberg, Christian
Deyell, Marc W.
author_sort Steinberg, Christian
collection PubMed
description Ibogaine is a psychoactive herbal medication with alleged antiaddiction properties. We report a case of ibogaine intoxication mimicking Long‐QT syndrome resulting in ventricular flutter and nearby cardiac arrest. A 61‐year‐old man experienced massive QT prolongation and ventricular flutter at a rate of 270 beats per minute requiring defibrillation after ingestion of a large dose of Ibogaine. The ingested dose of 65‐70 mg/kg represents the highest survived ibogaine dose reported to date. As a result of the long plasma half‐life of ibogaine, it took 7 days for the patient's QT interval to normalize.
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spelling pubmed-61114652018-08-30 Cardiac arrest after ibogaine intoxication Steinberg, Christian Deyell, Marc W. J Arrhythm Case Reports Ibogaine is a psychoactive herbal medication with alleged antiaddiction properties. We report a case of ibogaine intoxication mimicking Long‐QT syndrome resulting in ventricular flutter and nearby cardiac arrest. A 61‐year‐old man experienced massive QT prolongation and ventricular flutter at a rate of 270 beats per minute requiring defibrillation after ingestion of a large dose of Ibogaine. The ingested dose of 65‐70 mg/kg represents the highest survived ibogaine dose reported to date. As a result of the long plasma half‐life of ibogaine, it took 7 days for the patient's QT interval to normalize. John Wiley and Sons Inc. 2018-06-12 /pmc/articles/PMC6111465/ /pubmed/30167018 http://dx.doi.org/10.1002/joa3.12061 Text en © 2018 The Authors. Journal of Arrhythmia published by John Wiley & Sons Australia, Ltd on behalf of the Japanese Heart Rhythm Society. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Reports
Steinberg, Christian
Deyell, Marc W.
Cardiac arrest after ibogaine intoxication
title Cardiac arrest after ibogaine intoxication
title_full Cardiac arrest after ibogaine intoxication
title_fullStr Cardiac arrest after ibogaine intoxication
title_full_unstemmed Cardiac arrest after ibogaine intoxication
title_short Cardiac arrest after ibogaine intoxication
title_sort cardiac arrest after ibogaine intoxication
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111465/
https://www.ncbi.nlm.nih.gov/pubmed/30167018
http://dx.doi.org/10.1002/joa3.12061
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