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Epidemiological, clinical, and immunological profile of cases at the time of HIV testing (a clinic-based observational cross-sectional study)

INTRODUCTION: With the availability of free antiretroviral therapy (ART), HIV/AIDS has become a chronic manageable disease, but its transmission still continues. Early testing, though desirable, is still a far-fetched goal. MATERIALS AND METHODS: Forty-six newly detected HIV cases attending skin and...

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Autores principales: Marfatia, Yogesh S., Shah, Ruchi Jayeshbhai, Baxi, Reema Rajesh, Surani, Ashma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111640/
https://www.ncbi.nlm.nih.gov/pubmed/30187019
http://dx.doi.org/10.4103/ijstd.IJSTD_20_18
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author Marfatia, Yogesh S.
Shah, Ruchi Jayeshbhai
Baxi, Reema Rajesh
Surani, Ashma
author_facet Marfatia, Yogesh S.
Shah, Ruchi Jayeshbhai
Baxi, Reema Rajesh
Surani, Ashma
author_sort Marfatia, Yogesh S.
collection PubMed
description INTRODUCTION: With the availability of free antiretroviral therapy (ART), HIV/AIDS has become a chronic manageable disease, but its transmission still continues. Early testing, though desirable, is still a far-fetched goal. MATERIALS AND METHODS: Forty-six newly detected HIV cases attending skin and sexually transmitted disease (STD) outpatient department (OPD) were studied. Careful inquiry was made to know the reason for HIV testing, marital status, concordance rate in married couples, and CD4 count at the time of presentation. RESULTS: Of the 46 cases, 27 (59%) cases were in the age range of 20–40 years with 41% females and 59% males. Forty-one cases were married and cohabiting, out of which 19 were seroconcordant. Condom was used by 5/19 cases in seroconcordant group and 3/22 cases in serodiscordant group. Fourteen (30.4%) cases were tested for an epidemiologic reason (the most common being spouse positivity and antenatal care testing). Of the remaining 32 cases, the reason for testing was mucocutaneous manifestations in 16 cases, STD in 10 cases, and systemic illnesses (fever of unknown origin and weight loss) in 6 cases. Mean CD4 count was 336/cumm, with 17 cases having CD4 count <250/cumm. CONCLUSION: Except one, all cases were tested either because they were symptomatic or were referred by health-care provider for epidemiologic reasons. The presence of mucocutaneous manifestations including STD and systemic illnesses as the reason for testing as well as low CD4 count at the time of testing suggest less and late testing. Low condom use and high STD rate in married couple imply continued intramarital transmission. Although HIV seropositivity offers an entry point into continuum of comprehensive care package which includes free ART, it appears that HIV testing is still less and late.
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spelling pubmed-61116402018-09-05 Epidemiological, clinical, and immunological profile of cases at the time of HIV testing (a clinic-based observational cross-sectional study) Marfatia, Yogesh S. Shah, Ruchi Jayeshbhai Baxi, Reema Rajesh Surani, Ashma Indian J Sex Transm Dis AIDS Original Article INTRODUCTION: With the availability of free antiretroviral therapy (ART), HIV/AIDS has become a chronic manageable disease, but its transmission still continues. Early testing, though desirable, is still a far-fetched goal. MATERIALS AND METHODS: Forty-six newly detected HIV cases attending skin and sexually transmitted disease (STD) outpatient department (OPD) were studied. Careful inquiry was made to know the reason for HIV testing, marital status, concordance rate in married couples, and CD4 count at the time of presentation. RESULTS: Of the 46 cases, 27 (59%) cases were in the age range of 20–40 years with 41% females and 59% males. Forty-one cases were married and cohabiting, out of which 19 were seroconcordant. Condom was used by 5/19 cases in seroconcordant group and 3/22 cases in serodiscordant group. Fourteen (30.4%) cases were tested for an epidemiologic reason (the most common being spouse positivity and antenatal care testing). Of the remaining 32 cases, the reason for testing was mucocutaneous manifestations in 16 cases, STD in 10 cases, and systemic illnesses (fever of unknown origin and weight loss) in 6 cases. Mean CD4 count was 336/cumm, with 17 cases having CD4 count <250/cumm. CONCLUSION: Except one, all cases were tested either because they were symptomatic or were referred by health-care provider for epidemiologic reasons. The presence of mucocutaneous manifestations including STD and systemic illnesses as the reason for testing as well as low CD4 count at the time of testing suggest less and late testing. Low condom use and high STD rate in married couple imply continued intramarital transmission. Although HIV seropositivity offers an entry point into continuum of comprehensive care package which includes free ART, it appears that HIV testing is still less and late. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC6111640/ /pubmed/30187019 http://dx.doi.org/10.4103/ijstd.IJSTD_20_18 Text en Copyright: © 2018 Indian Journal of Sexually Transmitted Diseases and AIDS http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Marfatia, Yogesh S.
Shah, Ruchi Jayeshbhai
Baxi, Reema Rajesh
Surani, Ashma
Epidemiological, clinical, and immunological profile of cases at the time of HIV testing (a clinic-based observational cross-sectional study)
title Epidemiological, clinical, and immunological profile of cases at the time of HIV testing (a clinic-based observational cross-sectional study)
title_full Epidemiological, clinical, and immunological profile of cases at the time of HIV testing (a clinic-based observational cross-sectional study)
title_fullStr Epidemiological, clinical, and immunological profile of cases at the time of HIV testing (a clinic-based observational cross-sectional study)
title_full_unstemmed Epidemiological, clinical, and immunological profile of cases at the time of HIV testing (a clinic-based observational cross-sectional study)
title_short Epidemiological, clinical, and immunological profile of cases at the time of HIV testing (a clinic-based observational cross-sectional study)
title_sort epidemiological, clinical, and immunological profile of cases at the time of hiv testing (a clinic-based observational cross-sectional study)
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111640/
https://www.ncbi.nlm.nih.gov/pubmed/30187019
http://dx.doi.org/10.4103/ijstd.IJSTD_20_18
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