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Disruption of Planar Cell Polarity Pathway Attributable to Valproic Acid-Induced Congenital Heart Disease through Hdac3 Participation in Mice

BACKGROUND: Valproic acid (VPA) exposure during pregnancy has been proven to contribute to congenital heart disease (CHD). Our previous findings implied that disruption of planar cell polarity (PCP) signaling pathway in cardiomyocytes might be a factor for the cardiac teratogenesis of VPA. In additi...

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Detalles Bibliográficos
Autores principales:	Duan, Hong-Yu, Zhou, Kai-Yu, Wang, Tao, Zhang, Yi, Li, Yi-Fei, Hua, Yi-Min, Wang, Chuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111683/ https://www.ncbi.nlm.nih.gov/pubmed/30127218 http://dx.doi.org/10.4103/0366-6999.239311

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