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Actin cytoskeleton assembly regulates collagen production via TGF‐β type II receptor in human skin fibroblasts
The dermal compartment of skin is primarily composed of collagen‐rich extracellular matrix (ECM), which is produced by dermal fibroblasts. In Young skin, fibroblasts attach to the ECM through integrins. During ageing, fragmentation of the dermal ECM limits fibroblast attachment. This reduced attachm...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111811/ https://www.ncbi.nlm.nih.gov/pubmed/29888864 http://dx.doi.org/10.1111/jcmm.13685 |