Cargando…
Actin cytoskeleton assembly regulates collagen production via TGF‐β type II receptor in human skin fibroblasts
The dermal compartment of skin is primarily composed of collagen‐rich extracellular matrix (ECM), which is produced by dermal fibroblasts. In Young skin, fibroblasts attach to the ECM through integrins. During ageing, fragmentation of the dermal ECM limits fibroblast attachment. This reduced attachm...
Autores principales: | Qin, Zhaoping, Fisher, Gary J., Voorhees, John J., Quan, Taihao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111811/ https://www.ncbi.nlm.nih.gov/pubmed/29888864 http://dx.doi.org/10.1111/jcmm.13685 |
Ejemplares similares
Ejemplares similares
-
Reduction of fibroblast size/mechanical force down‐regulates TGF‐β type II receptor: implications for human skin aging
por: Fisher, Gary J., et al.
Publicado: (2015) -
YAP/TAZ regulates TGF-β/Smad3 signaling by induction of Smad7 via AP-1 in human skin dermal fibroblasts
por: Qin, Zhaoping, et al.
Publicado: (2018) -
Age-associated reduction of cellular spreading/mechanical force up-regulates matrix metalloproteinase-1 expression and collagen fibril fragmentation via c-Jun/AP-1 in human dermal fibroblasts
por: Qin, Zhaoping, et al.
Publicado: (2014) -
Oxidant Exposure Induces Cysteine-Rich Protein 61 (CCN1) via c-Jun/AP-1 to Reduce Collagen Expression in Human Dermal Fibroblasts
por: Qin, Zhaoping, et al.
Publicado: (2014) -
Elevated Matrix Metalloproteinases and Collagen Fragmentation in Photodamaged Human Skin: Impact of Altered Extracellular Matrix Microenvironment on Dermal Fibroblast Function
por: Quan, Taihao, et al.
Publicado: (2013)