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Curcumin prevents the bile reflux‐induced NF‐κB‐related mRNA oncogenic phenotype, in human hypopharyngeal cells

The presence of bile is not an uncommon finding in acidic oesophageal and extra‐oesophageal refluxate, possibly affecting the hypopharyngeal mucosa and leading to neoplastic events. We recently demonstrated that acidic bile (pH ≤ 4.0) can induce NF‐κB activation and oncogenic mRNA phenotype in norma...

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Detalles Bibliográficos
Autores principales: Vageli, Dimitra P., Doukas, Sotirios G., Spock, Todd, Sasaki, Clarence T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111812/
https://www.ncbi.nlm.nih.gov/pubmed/29911313
http://dx.doi.org/10.1111/jcmm.13701