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Butyrate Protects Mice Against Methionine–Choline-Deficient Diet-Induced Non-alcoholic Steatohepatitis by Improving Gut Barrier Function, Attenuating Inflammation and Reducing Endotoxin Levels
Butyrate exerts protective effects against non-alcoholic steatohepatitis (NASH), but the underlying mechanisms are unclear. We aimed to investigate the role of butyrate-induced gut microbiota and metabolism in NASH development. Sixty-five C57BL/6J mice were divided into four groups (n = 15–17 per gr...
Autores principales: | Ye, Jianzhong, Lv, Longxian, Wu, Wenrui, Li, Yating, Shi, Ding, Fang, Daiqiong, Guo, Feifei, Jiang, Huiyong, Yan, Ren, Ye, Wanchun, Li, Lanjuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111843/ https://www.ncbi.nlm.nih.gov/pubmed/30186272 http://dx.doi.org/10.3389/fmicb.2018.01967 |
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