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Kallistatin attenuates endothelial senescence by modulating Let‐7g‐mediated miR‐34a‐SIRT1‐eNOS pathway

Kallistatin, a plasma protein, protects against vascular and organ injury. This study is aimed to investigate the role and mechanism of kallistatin in endothelial senescence. Kallistatin inhibited H(2)O(2)‐induced senescence in human endothelial cells, as indicated by reduced senescence‐associated‐β...

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Detalles Bibliográficos
Autores principales: Guo, Youming, Chao, Lee, Chao, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111868/
https://www.ncbi.nlm.nih.gov/pubmed/29992759
http://dx.doi.org/10.1111/jcmm.13734

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