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Kallistatin attenuates endothelial senescence by modulating Let‐7g‐mediated miR‐34a‐SIRT1‐eNOS pathway
Kallistatin, a plasma protein, protects against vascular and organ injury. This study is aimed to investigate the role and mechanism of kallistatin in endothelial senescence. Kallistatin inhibited H(2)O(2)‐induced senescence in human endothelial cells, as indicated by reduced senescence‐associated‐β...
Autores principales: | Guo, Youming, Chao, Lee, Chao, Julie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111868/ https://www.ncbi.nlm.nih.gov/pubmed/29992759 http://dx.doi.org/10.1111/jcmm.13734 |
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