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Potential Point-of-Care Microfluidic Devices to Diagnose Iron Deficiency Anemia

Over the past 20 years, rapid technological advancement in the field of microfluidics has produced a wide array of microfluidic point-of-care (POC) diagnostic devices for the healthcare industry. However, potential microfluidic applications in the field of nutrition, specifically to diagnose iron de...

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Detalles Bibliográficos
Autores principales: Yap, Boon Kar, M.Soair, Siti Nur’Arifah, Talik, Noor Azrina, Lim, Wai Feng, Mei I, Lai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111990/
https://www.ncbi.nlm.nih.gov/pubmed/30103424
http://dx.doi.org/10.3390/s18082625
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author Yap, Boon Kar
M.Soair, Siti Nur’Arifah
Talik, Noor Azrina
Lim, Wai Feng
Mei I, Lai
author_facet Yap, Boon Kar
M.Soair, Siti Nur’Arifah
Talik, Noor Azrina
Lim, Wai Feng
Mei I, Lai
author_sort Yap, Boon Kar
collection PubMed
description Over the past 20 years, rapid technological advancement in the field of microfluidics has produced a wide array of microfluidic point-of-care (POC) diagnostic devices for the healthcare industry. However, potential microfluidic applications in the field of nutrition, specifically to diagnose iron deficiency anemia (IDA) detection, remain scarce. Iron deficiency anemia is the most common form of anemia, which affects billions of people globally, especially the elderly, women, and children. This review comprehensively analyzes the current diagnosis technologies that address anemia-related IDA-POC microfluidic devices in the future. This review briefly highlights various microfluidics devices that have the potential to detect IDA and discusses some commercially available devices for blood plasma separation mechanisms. Reagent deposition and integration into microfluidic devices are also explored. Finally, we discuss the challenges of insights into potential portable microfluidic systems, especially for remote IDA detection.
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spelling pubmed-61119902018-08-30 Potential Point-of-Care Microfluidic Devices to Diagnose Iron Deficiency Anemia Yap, Boon Kar M.Soair, Siti Nur’Arifah Talik, Noor Azrina Lim, Wai Feng Mei I, Lai Sensors (Basel) Review Over the past 20 years, rapid technological advancement in the field of microfluidics has produced a wide array of microfluidic point-of-care (POC) diagnostic devices for the healthcare industry. However, potential microfluidic applications in the field of nutrition, specifically to diagnose iron deficiency anemia (IDA) detection, remain scarce. Iron deficiency anemia is the most common form of anemia, which affects billions of people globally, especially the elderly, women, and children. This review comprehensively analyzes the current diagnosis technologies that address anemia-related IDA-POC microfluidic devices in the future. This review briefly highlights various microfluidics devices that have the potential to detect IDA and discusses some commercially available devices for blood plasma separation mechanisms. Reagent deposition and integration into microfluidic devices are also explored. Finally, we discuss the challenges of insights into potential portable microfluidic systems, especially for remote IDA detection. MDPI 2018-08-10 /pmc/articles/PMC6111990/ /pubmed/30103424 http://dx.doi.org/10.3390/s18082625 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Yap, Boon Kar
M.Soair, Siti Nur’Arifah
Talik, Noor Azrina
Lim, Wai Feng
Mei I, Lai
Potential Point-of-Care Microfluidic Devices to Diagnose Iron Deficiency Anemia
title Potential Point-of-Care Microfluidic Devices to Diagnose Iron Deficiency Anemia
title_full Potential Point-of-Care Microfluidic Devices to Diagnose Iron Deficiency Anemia
title_fullStr Potential Point-of-Care Microfluidic Devices to Diagnose Iron Deficiency Anemia
title_full_unstemmed Potential Point-of-Care Microfluidic Devices to Diagnose Iron Deficiency Anemia
title_short Potential Point-of-Care Microfluidic Devices to Diagnose Iron Deficiency Anemia
title_sort potential point-of-care microfluidic devices to diagnose iron deficiency anemia
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111990/
https://www.ncbi.nlm.nih.gov/pubmed/30103424
http://dx.doi.org/10.3390/s18082625
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