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Potential Point-of-Care Microfluidic Devices to Diagnose Iron Deficiency Anemia
Over the past 20 years, rapid technological advancement in the field of microfluidics has produced a wide array of microfluidic point-of-care (POC) diagnostic devices for the healthcare industry. However, potential microfluidic applications in the field of nutrition, specifically to diagnose iron de...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111990/ https://www.ncbi.nlm.nih.gov/pubmed/30103424 http://dx.doi.org/10.3390/s18082625 |
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author | Yap, Boon Kar M.Soair, Siti Nur’Arifah Talik, Noor Azrina Lim, Wai Feng Mei I, Lai |
author_facet | Yap, Boon Kar M.Soair, Siti Nur’Arifah Talik, Noor Azrina Lim, Wai Feng Mei I, Lai |
author_sort | Yap, Boon Kar |
collection | PubMed |
description | Over the past 20 years, rapid technological advancement in the field of microfluidics has produced a wide array of microfluidic point-of-care (POC) diagnostic devices for the healthcare industry. However, potential microfluidic applications in the field of nutrition, specifically to diagnose iron deficiency anemia (IDA) detection, remain scarce. Iron deficiency anemia is the most common form of anemia, which affects billions of people globally, especially the elderly, women, and children. This review comprehensively analyzes the current diagnosis technologies that address anemia-related IDA-POC microfluidic devices in the future. This review briefly highlights various microfluidics devices that have the potential to detect IDA and discusses some commercially available devices for blood plasma separation mechanisms. Reagent deposition and integration into microfluidic devices are also explored. Finally, we discuss the challenges of insights into potential portable microfluidic systems, especially for remote IDA detection. |
format | Online Article Text |
id | pubmed-6111990 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-61119902018-08-30 Potential Point-of-Care Microfluidic Devices to Diagnose Iron Deficiency Anemia Yap, Boon Kar M.Soair, Siti Nur’Arifah Talik, Noor Azrina Lim, Wai Feng Mei I, Lai Sensors (Basel) Review Over the past 20 years, rapid technological advancement in the field of microfluidics has produced a wide array of microfluidic point-of-care (POC) diagnostic devices for the healthcare industry. However, potential microfluidic applications in the field of nutrition, specifically to diagnose iron deficiency anemia (IDA) detection, remain scarce. Iron deficiency anemia is the most common form of anemia, which affects billions of people globally, especially the elderly, women, and children. This review comprehensively analyzes the current diagnosis technologies that address anemia-related IDA-POC microfluidic devices in the future. This review briefly highlights various microfluidics devices that have the potential to detect IDA and discusses some commercially available devices for blood plasma separation mechanisms. Reagent deposition and integration into microfluidic devices are also explored. Finally, we discuss the challenges of insights into potential portable microfluidic systems, especially for remote IDA detection. MDPI 2018-08-10 /pmc/articles/PMC6111990/ /pubmed/30103424 http://dx.doi.org/10.3390/s18082625 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Yap, Boon Kar M.Soair, Siti Nur’Arifah Talik, Noor Azrina Lim, Wai Feng Mei I, Lai Potential Point-of-Care Microfluidic Devices to Diagnose Iron Deficiency Anemia |
title | Potential Point-of-Care Microfluidic Devices to Diagnose Iron Deficiency Anemia |
title_full | Potential Point-of-Care Microfluidic Devices to Diagnose Iron Deficiency Anemia |
title_fullStr | Potential Point-of-Care Microfluidic Devices to Diagnose Iron Deficiency Anemia |
title_full_unstemmed | Potential Point-of-Care Microfluidic Devices to Diagnose Iron Deficiency Anemia |
title_short | Potential Point-of-Care Microfluidic Devices to Diagnose Iron Deficiency Anemia |
title_sort | potential point-of-care microfluidic devices to diagnose iron deficiency anemia |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111990/ https://www.ncbi.nlm.nih.gov/pubmed/30103424 http://dx.doi.org/10.3390/s18082625 |
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