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Antidepressant Effects of Probucol on Early-Symptomatic YAC128 Transgenic Mice for Huntington's Disease

Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused by a trinucleotide expansion in the HD gene, resulting in an extended polyglutamine tract in the protein huntingtin. HD is traditionally viewed as a movement disorder, but cognitive and neuropsychiatric symptom...

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Detalles Bibliográficos
Autores principales:	de Paula Nascimento-Castro, Cristine, Wink, Ana Claudia, da Fônseca, Victor Silva, Bianco, Claudia Daniele, Winkelmann-Duarte, Elisa C., Farina, Marcelo, Rodrigues, Ana Lúcia S., Gil-Mohapel, Joana, de Bem, Andreza Fabro, Brocardo, Patricia S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112232/ https://www.ncbi.nlm.nih.gov/pubmed/30186318 http://dx.doi.org/10.1155/2018/4056383

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