Using LC–MS/MS-based targeted proteomics to monitor the pattern of ABC transporters expression in the development of drug resistance

PURPOSE: The overexpression of ATP-binding cassette transporters (ABC transporters), mainly including permeability glycoproteins (P-gp), multidrug resistance (MDR)-related protein 1 (MRP1), and breast cancer resistance proteins (BCRP), is one of the main reasons for the development of MDR which dire...

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Detalles Bibliográficos
Autores principales: Meng, Fanqi, Zou, Le, Zhang, Tengyu, Jiang, Lei, Ding, Yao, Yu, Peng, Peng, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112789/
https://www.ncbi.nlm.nih.gov/pubmed/30197538
http://dx.doi.org/10.2147/CMAR.S164766

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