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New corneal assessment index from the relational thickness and other OCULUS values (CAIRO Index)

PURPOSE: The aim of this study was to find indices for keratoconus (KC) detection with higher sensitivity and specificity than the currently available ones with the rotating Scheimpflug imaging (Oculyzer I, Pentacam) software. PATIENTS AND METHODS: Data of 103 normal and 73 KC eyes imaged by Oculyze...

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Autores principales: Roshdy, Maged M, Wahba, Sherine S, Fikry, Ramy R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112792/
https://www.ncbi.nlm.nih.gov/pubmed/30197498
http://dx.doi.org/10.2147/OPTH.S171827
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author Roshdy, Maged M
Wahba, Sherine S
Fikry, Ramy R
author_facet Roshdy, Maged M
Wahba, Sherine S
Fikry, Ramy R
author_sort Roshdy, Maged M
collection PubMed
description PURPOSE: The aim of this study was to find indices for keratoconus (KC) detection with higher sensitivity and specificity than the currently available ones with the rotating Scheimpflug imaging (Oculyzer I, Pentacam) software. PATIENTS AND METHODS: Data of 103 normal and 73 KC eyes imaged by Oculyzer I, including slit-lamp examination, refraction, Scheimpflug images, and follow-up data were collected. Logistic regression was done to find new indices with higher area under receiver operating characteristic curves using the currently available ones. RESULTS: The Corneal Assessment Index from Relational thickness and other OCULUS Values 9 (CAIRO 9) index, deduced from the Ambrosio relational thickness-maximum and the anterior elevation at thinnest point from 9 mm best-fit sphere, and the CAIRO 8, deduced from Ambrosio relational thickness-maximum and anterior elevation at thinnest point from 8 mm best-fit sphere, have a very high area under receiver operating characteristic curves for KC detection (0.997 and 0.995, respectively). CONCLUSION: New corneal assessment index is deduced with better sensitivity and specificity for KC detection.
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spelling pubmed-61127922018-09-07 New corneal assessment index from the relational thickness and other OCULUS values (CAIRO Index) Roshdy, Maged M Wahba, Sherine S Fikry, Ramy R Clin Ophthalmol Original Research PURPOSE: The aim of this study was to find indices for keratoconus (KC) detection with higher sensitivity and specificity than the currently available ones with the rotating Scheimpflug imaging (Oculyzer I, Pentacam) software. PATIENTS AND METHODS: Data of 103 normal and 73 KC eyes imaged by Oculyzer I, including slit-lamp examination, refraction, Scheimpflug images, and follow-up data were collected. Logistic regression was done to find new indices with higher area under receiver operating characteristic curves using the currently available ones. RESULTS: The Corneal Assessment Index from Relational thickness and other OCULUS Values 9 (CAIRO 9) index, deduced from the Ambrosio relational thickness-maximum and the anterior elevation at thinnest point from 9 mm best-fit sphere, and the CAIRO 8, deduced from Ambrosio relational thickness-maximum and anterior elevation at thinnest point from 8 mm best-fit sphere, have a very high area under receiver operating characteristic curves for KC detection (0.997 and 0.995, respectively). CONCLUSION: New corneal assessment index is deduced with better sensitivity and specificity for KC detection. Dove Medical Press 2018-08-23 /pmc/articles/PMC6112792/ /pubmed/30197498 http://dx.doi.org/10.2147/OPTH.S171827 Text en © 2018 Roshdy et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Original Research
Roshdy, Maged M
Wahba, Sherine S
Fikry, Ramy R
New corneal assessment index from the relational thickness and other OCULUS values (CAIRO Index)
title New corneal assessment index from the relational thickness and other OCULUS values (CAIRO Index)
title_full New corneal assessment index from the relational thickness and other OCULUS values (CAIRO Index)
title_fullStr New corneal assessment index from the relational thickness and other OCULUS values (CAIRO Index)
title_full_unstemmed New corneal assessment index from the relational thickness and other OCULUS values (CAIRO Index)
title_short New corneal assessment index from the relational thickness and other OCULUS values (CAIRO Index)
title_sort new corneal assessment index from the relational thickness and other oculus values (cairo index)
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112792/
https://www.ncbi.nlm.nih.gov/pubmed/30197498
http://dx.doi.org/10.2147/OPTH.S171827
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