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New corneal assessment index from the relational thickness and other OCULUS values (CAIRO Index)
PURPOSE: The aim of this study was to find indices for keratoconus (KC) detection with higher sensitivity and specificity than the currently available ones with the rotating Scheimpflug imaging (Oculyzer I, Pentacam) software. PATIENTS AND METHODS: Data of 103 normal and 73 KC eyes imaged by Oculyze...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112792/ https://www.ncbi.nlm.nih.gov/pubmed/30197498 http://dx.doi.org/10.2147/OPTH.S171827 |
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author | Roshdy, Maged M Wahba, Sherine S Fikry, Ramy R |
author_facet | Roshdy, Maged M Wahba, Sherine S Fikry, Ramy R |
author_sort | Roshdy, Maged M |
collection | PubMed |
description | PURPOSE: The aim of this study was to find indices for keratoconus (KC) detection with higher sensitivity and specificity than the currently available ones with the rotating Scheimpflug imaging (Oculyzer I, Pentacam) software. PATIENTS AND METHODS: Data of 103 normal and 73 KC eyes imaged by Oculyzer I, including slit-lamp examination, refraction, Scheimpflug images, and follow-up data were collected. Logistic regression was done to find new indices with higher area under receiver operating characteristic curves using the currently available ones. RESULTS: The Corneal Assessment Index from Relational thickness and other OCULUS Values 9 (CAIRO 9) index, deduced from the Ambrosio relational thickness-maximum and the anterior elevation at thinnest point from 9 mm best-fit sphere, and the CAIRO 8, deduced from Ambrosio relational thickness-maximum and anterior elevation at thinnest point from 8 mm best-fit sphere, have a very high area under receiver operating characteristic curves for KC detection (0.997 and 0.995, respectively). CONCLUSION: New corneal assessment index is deduced with better sensitivity and specificity for KC detection. |
format | Online Article Text |
id | pubmed-6112792 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-61127922018-09-07 New corneal assessment index from the relational thickness and other OCULUS values (CAIRO Index) Roshdy, Maged M Wahba, Sherine S Fikry, Ramy R Clin Ophthalmol Original Research PURPOSE: The aim of this study was to find indices for keratoconus (KC) detection with higher sensitivity and specificity than the currently available ones with the rotating Scheimpflug imaging (Oculyzer I, Pentacam) software. PATIENTS AND METHODS: Data of 103 normal and 73 KC eyes imaged by Oculyzer I, including slit-lamp examination, refraction, Scheimpflug images, and follow-up data were collected. Logistic regression was done to find new indices with higher area under receiver operating characteristic curves using the currently available ones. RESULTS: The Corneal Assessment Index from Relational thickness and other OCULUS Values 9 (CAIRO 9) index, deduced from the Ambrosio relational thickness-maximum and the anterior elevation at thinnest point from 9 mm best-fit sphere, and the CAIRO 8, deduced from Ambrosio relational thickness-maximum and anterior elevation at thinnest point from 8 mm best-fit sphere, have a very high area under receiver operating characteristic curves for KC detection (0.997 and 0.995, respectively). CONCLUSION: New corneal assessment index is deduced with better sensitivity and specificity for KC detection. Dove Medical Press 2018-08-23 /pmc/articles/PMC6112792/ /pubmed/30197498 http://dx.doi.org/10.2147/OPTH.S171827 Text en © 2018 Roshdy et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Original Research Roshdy, Maged M Wahba, Sherine S Fikry, Ramy R New corneal assessment index from the relational thickness and other OCULUS values (CAIRO Index) |
title | New corneal assessment index from the relational thickness and other OCULUS values (CAIRO Index) |
title_full | New corneal assessment index from the relational thickness and other OCULUS values (CAIRO Index) |
title_fullStr | New corneal assessment index from the relational thickness and other OCULUS values (CAIRO Index) |
title_full_unstemmed | New corneal assessment index from the relational thickness and other OCULUS values (CAIRO Index) |
title_short | New corneal assessment index from the relational thickness and other OCULUS values (CAIRO Index) |
title_sort | new corneal assessment index from the relational thickness and other oculus values (cairo index) |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112792/ https://www.ncbi.nlm.nih.gov/pubmed/30197498 http://dx.doi.org/10.2147/OPTH.S171827 |
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