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Synergistic antitumoral efficacy of a novel replicative adenovirus SG611-PDCD5 and daunorubicin in human leukemic cells

BACKGROUND: Daunorubicin is a traditional chemotherapeutic agent that plays a pivotal role in leukemia therapy. However, the dose-related toxicity remains a considerable challenge. The apoptosis-regulating gene, PDCD5, is downregulated in various tumors, including leukemias, and may provide a potent...

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Detalles Bibliográficos
Autores principales:	Zhou, Ya-Lan, Yao, Qiu-Mei, Zhou, Jiao, Chang, Yan, Li, Jin-Lan, Wang, Ya-Zhe, Wu, Hong-Ping, Chen, Yu-Hong, Liu, Yan-Rong, Huang, Xiao-Jun, Ruan, Guo-Rui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112794/ https://www.ncbi.nlm.nih.gov/pubmed/30197523 http://dx.doi.org/10.2147/OTT.S167868

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