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The atomic structure of a eukaryotic oligosaccharyl transferase complex

N-glycosylation is a ubiquitous modification of eukaryotic secretory and membrane-bound proteins; about 90% of glycoproteins are N-glycosylated. The reaction is catalyzed by an eight-protein oligosaccharyltransferase complex, OST, embedded in the ER membrane. Our understanding of eukaryotic protein...

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Detalles Bibliográficos
Autores principales: Bai, Lin, Wang, Tong, Zhao, Gongpu, Kovach, Amanda, Li, Huilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112861/
https://www.ncbi.nlm.nih.gov/pubmed/29466327
http://dx.doi.org/10.1038/nature25755