Altered exocrine function can drive adipose wasting in early pancreatic cancer

Changes in cell and organismal metabolism accompany malignancy(1,2). Pancreatic ductal adenocarcinoma (PDAC) is associated with peripheral tissue wasting, a metabolic syndrome that lowers quality of life and is proposed to decrease cancer patient survival(3,4). Tissue wasting is a multifactorial dis...

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Detalles Bibliográficos
Autores principales: Danai, Laura V., Babic, Ana, Rosenthal, Michael H., Dennstedt, Emily, Muir, Alexander, Lien, Evan C., Mayers, Jared R., Tai, Karen, Lau, Allison N., Jones-Sali, Paul, Prado, Carla M., Petersen, Gloria M., Takahashi, Naoki, Sugimoto, Motokazu, Yeh, Jen Jen, Lopez, Nicole, Bardeesy, Nabeel, Fernandez-del Castillo, Carlos, Liss, Andrew S., Koong, Albert C., Bui, Justin, Yuan, Chen, Welch, Marisa W., Brais, Lauren K., Kulke, Matthew H., Dennis, Courtney, Clish, Clary B., Wolpin, Brian M., Heiden, Matthew Vander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112987/
https://www.ncbi.nlm.nih.gov/pubmed/29925948
http://dx.doi.org/10.1038/s41586-018-0235-7

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