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Clinical analysis of 86 botulism cases caused by cosmetic injection of botulinum toxin (BoNT)
This study was conducted to analyze the clinical characteristics of and treatment strategies for botulism among patients receiving cosmetic injection of botulinum toxin (BoNT). A total of 86 botulism patients caused by cosmetic injection of BoNT were enrolled in our study. All of the patients were d...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112997/ https://www.ncbi.nlm.nih.gov/pubmed/30142749 http://dx.doi.org/10.1097/MD.0000000000010659 |
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author | Bai, Lili Peng, Xiaobo Liu, Yanqing Sun, Yawei Wang, Xin Wang, Xingwang Lin, Guodong Zhang, Peng Wan, Kun Qiu, Zewu |
author_facet | Bai, Lili Peng, Xiaobo Liu, Yanqing Sun, Yawei Wang, Xin Wang, Xingwang Lin, Guodong Zhang, Peng Wan, Kun Qiu, Zewu |
author_sort | Bai, Lili |
collection | PubMed |
description | This study was conducted to analyze the clinical characteristics of and treatment strategies for botulism among patients receiving cosmetic injection of botulinum toxin (BoNT). A total of 86 botulism patients caused by cosmetic injection of BoNT were enrolled in our study. All of the patients were diagnosed according to their history of cosmetic BoNT injection, clinical symptoms and signs, and other auxiliary examinations (including those on renal and liver functions, blood index detection, and chest X-ray). All of the patients received comprehensive treatments and botulinum antitoxin serum injection. The main symptoms of botulism patients included headache, dizziness, insomnia, fatigue, blurred vision, eye opening difficulty, slurred speech, dysphagia, bucking, constipation, and anxiety. These clinical symptoms occurred 0∼36 days after BoNT injection, especially from 2nd to 6th day after the operation. Furthermore, the usage dose of BoNT was negatively related to latent period. Finally, patients all discharged from our hospital 1∼20 days after treatments, and their symptoms relieved or disappeared. Botulism is a severe side effect for BoNT injection. Injecting botulinum antitoxin serum may be an effective approach to improve clinical outcomes of botulism cases. |
format | Online Article Text |
id | pubmed-6112997 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-61129972018-09-07 Clinical analysis of 86 botulism cases caused by cosmetic injection of botulinum toxin (BoNT) Bai, Lili Peng, Xiaobo Liu, Yanqing Sun, Yawei Wang, Xin Wang, Xingwang Lin, Guodong Zhang, Peng Wan, Kun Qiu, Zewu Medicine (Baltimore) Research Article This study was conducted to analyze the clinical characteristics of and treatment strategies for botulism among patients receiving cosmetic injection of botulinum toxin (BoNT). A total of 86 botulism patients caused by cosmetic injection of BoNT were enrolled in our study. All of the patients were diagnosed according to their history of cosmetic BoNT injection, clinical symptoms and signs, and other auxiliary examinations (including those on renal and liver functions, blood index detection, and chest X-ray). All of the patients received comprehensive treatments and botulinum antitoxin serum injection. The main symptoms of botulism patients included headache, dizziness, insomnia, fatigue, blurred vision, eye opening difficulty, slurred speech, dysphagia, bucking, constipation, and anxiety. These clinical symptoms occurred 0∼36 days after BoNT injection, especially from 2nd to 6th day after the operation. Furthermore, the usage dose of BoNT was negatively related to latent period. Finally, patients all discharged from our hospital 1∼20 days after treatments, and their symptoms relieved or disappeared. Botulism is a severe side effect for BoNT injection. Injecting botulinum antitoxin serum may be an effective approach to improve clinical outcomes of botulism cases. Wolters Kluwer Health 2018-08-24 /pmc/articles/PMC6112997/ /pubmed/30142749 http://dx.doi.org/10.1097/MD.0000000000010659 Text en Copyright © 2018 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0 |
spellingShingle | Research Article Bai, Lili Peng, Xiaobo Liu, Yanqing Sun, Yawei Wang, Xin Wang, Xingwang Lin, Guodong Zhang, Peng Wan, Kun Qiu, Zewu Clinical analysis of 86 botulism cases caused by cosmetic injection of botulinum toxin (BoNT) |
title | Clinical analysis of 86 botulism cases caused by cosmetic injection of botulinum toxin (BoNT) |
title_full | Clinical analysis of 86 botulism cases caused by cosmetic injection of botulinum toxin (BoNT) |
title_fullStr | Clinical analysis of 86 botulism cases caused by cosmetic injection of botulinum toxin (BoNT) |
title_full_unstemmed | Clinical analysis of 86 botulism cases caused by cosmetic injection of botulinum toxin (BoNT) |
title_short | Clinical analysis of 86 botulism cases caused by cosmetic injection of botulinum toxin (BoNT) |
title_sort | clinical analysis of 86 botulism cases caused by cosmetic injection of botulinum toxin (bont) |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112997/ https://www.ncbi.nlm.nih.gov/pubmed/30142749 http://dx.doi.org/10.1097/MD.0000000000010659 |
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