AMP Kinase Promotes Glioblastoma Bioenergetics and Tumor Growth

Stress is integral to tumor evolution, and cancer cell survival depends on stress management. We found that cancer-associated stress chronically activate the bioenergetic sensor AMP kinase (AMPK), and tumor cells hijack an AMPK-regulated stress response pathway conserved in normal cells, to survive....

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Detalles Bibliográficos
Autores principales: Chhipa, Rishi Raj, Fan, Qiang, Anderson, Jane, Muraleedharan, Ranjithmenon, Huang, Yan, Ciraolo, Georgianne, Chen, Xiaoting, Waclaw, Ronald, Chow, Lionel M., Khuchua, Zaza, Kofron, Matthew, Weirauch, Matthew T., Kendler, Ady, McPherson, Christopher, Ratner, Nancy, Nakano, Ichiro, Dasgupta, Nupur, Komurov, Kakajan, Dasgupta, Biplab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113057/
https://www.ncbi.nlm.nih.gov/pubmed/29915361
http://dx.doi.org/10.1038/s41556-018-0126-z

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