PARP12 (ARTD12) suppresses hepatocellular carcinoma metastasis through interacting with FHL2 and regulating its stability

PARP12 is a mono-ADP-ribosyltransferase, but its function remains largely unknown. Here, we identified four-and-a-half LIM-only protein 2 (FHL2) as a functional partner of PARP12 through protein affinity purification. Although PARP12 did not mono-ADP-ribosylate FHL2 in vitro and in vivo, PARP12 defi...

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Detalles Bibliográficos
Autores principales: Shao, Changjuan, Qiu, Yangyang, Liu, Juan, Feng, Huan, Shen, Suqin, Saiyin, Hexige, Yu, Wenbo, Wei, Youheng, Yu, Long, Su, Wei, Wu, Jiaxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113207/
https://www.ncbi.nlm.nih.gov/pubmed/30154409
http://dx.doi.org/10.1038/s41419-018-0906-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113207/
https://www.ncbi.nlm.nih.gov/pubmed/30154409
http://dx.doi.org/10.1038/s41419-018-0906-1

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