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Overexpression of homeodomain-interacting protein kinase 2 (HIPK2) attenuates sepsis-mediated liver injury by restoring autophagy

Sepsis is the leading cause of death in intensive care units worldwide. Autophagy has recently been shown to protect against sepsis-induced liver injury. Here, we investigated the roles of homeodomain-interacting protein kinase 2 (HIPK2) in the molecular mechanism of sepsis-induced liver injury. HIP...

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Detalles Bibliográficos
Autores principales: Jiang, Zhengyu, Bo, Lulong, Meng, Yan, Wang, Chen, Chen, Tianxing, Wang, Changli, Yu, Xiya, Deng, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113252/
https://www.ncbi.nlm.nih.gov/pubmed/30154452
http://dx.doi.org/10.1038/s41419-018-0838-9