Cargando…

JAZF1 ameliorates age and diet-associated hepatic steatosis through SREBP-1c -dependent mechanism

JAZF zinc finger 1 (JAZF1) is involved in glucose and lipid metabolisms. However, its role in aging- and nutrient-related hepatic steatosis is unclear. In the current study, we demonstrated that JAZF1 expression was markedly down-regulated in obesity-associated mice and nonalcoholic fatty liver dise...

Descripción completa

Detalles Bibliográficos
Autores principales: Wei, Qin, Zhou, Baoyong, Yang, Gangyi, Hu, Wenjing, Zhang, Lili, Liu, Rui, Li, Minyan, Wang, Kuan, Gu, Harvest F., Guan, Youfei, Zhu, Zhiming, Zheng, Hongting, Peng, Jun, Li, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113258/
https://www.ncbi.nlm.nih.gov/pubmed/30154417
http://dx.doi.org/10.1038/s41419-018-0923-0