March1-dependent modulation of donor MHC II on CD103(+) dendritic cells mitigates alloimmunity

In transplantation, donor dendritic cells (do-DCs) initiate the alloimmune response either by direct interaction with host T cells or by transferring intact donor MHC to host DCs. However, how do-DCs can be targeted for improving allograft survival is still unclear. Here we show CD103(+) DCs are the...

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Detalles Bibliográficos
Autores principales: Borges, Thiago J., Murakami, Naoka, Machado, Felipe D., Murshid, Ayesha, Lang, Benjamin J., Lopes, Rafael L., Bellan, Laura M., Uehara, Mayuko, Antunes, Krist H., Pérez-Saéz, Maria José, Birrane, Gabriel, Vianna, Priscila, Gonçalves, João Ismael B., Zanin, Rafael F., Azzi, Jamil, Abdi, Reza, Ishido, Satoshi, Shin, Jeoung-Sook, Souza, Ana Paula D., Calderwood, Stuart K., Riella, Leonardo V., Bonorino, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113260/
https://www.ncbi.nlm.nih.gov/pubmed/30154416
http://dx.doi.org/10.1038/s41467-018-05572-z

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