Cargando…

Recombinant milk fat globule-EGF factor-8 reduces apoptosis via integrin β3/FAK/PI3K/AKT signaling pathway in rats after traumatic brain injury

Accumulating evidence suggests neuronal apoptosis has the potential to lead to more harmful effects in the pathological processes following traumatic brain injury (TBI). Previous studies have established that milk fat globule-EGF factor-8 (MFG-E8) provides neuroprotection through modulation of infla...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gao, Yong-Yue, Zhang, Zi-Huan, Zhuang, Zong, Lu, Yue, Wu, Ling-Yun, Ye, Zhen-nan, Zhang, Xiang-Sheng, Chen, Chun-Lei, Li, Wei, Hang, Chun-Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113274/ https://www.ncbi.nlm.nih.gov/pubmed/30154436 http://dx.doi.org/10.1038/s41419-018-0939-5

Ejemplares similares

Milk fat globule EGF factor 8 restores mitochondrial function via integrin‐medicated activation of the FAK‐STAT3 signaling pathway in acute pancreatitis
por: Ren, Yifan, et al.
Publicado: (2021)

Oxymatrine reverses epithelial-mesenchymal transition in breast cancer cells by depressing α(Ⅴ)β(3) integrin/FAK/PI3K/Akt signaling activation
por: Chen, Yan, et al.
Publicado: (2019)

Milk Fat Globule-EGF Factor 8 Contributes to Progression of Hepatocellular Carcinoma
por: Ko, Duck Sung, et al.
Publicado: (2020)

Truncated Milk Fat Globule-EGF-like Factor 8 Ameliorates Liver Fibrosis via Inhibition of Integrin-TGFβ Receptor Interaction
por: An, Geun Ho, et al.
Publicado: (2021)

Albumin fibrillization induces apoptosis via integrin/FAK/Akt pathway
por: Huang, Chun-Yung, et al.
Publicado: (2009)

The neuroprotective effects of milk fat globule-EGF factor 8 against oligomeric amyloid β toxicity
por: Li, Endong, et al.
Publicado: (2012)

Serum milk fat globule-EGF factor 8 protein as a potential biomarker for metabolic syndrome
por: Lee, Han Ah, et al.
Publicado: (2021)

Enhancement of Zyxin Promotes Skin Fibrosis by Regulating FAK/PI3K/AKT and TGF-β Signaling Pathways via Integrins
por: Huang, Yan, et al.
Publicado: (2023)

Reduction in milk fat globule-EGF factor 8 inhibits triple-negative breast cancer cell viability and migration
por: Yang, Yong, et al.
Publicado: (2019)

Recombinant human milk fat globule-EGF factor VIII (rhMFG-E8) as a therapy for sepsis after acute exposure to alcohol
por: Chaung, Wayne W., et al.
Publicado: (2019)

14, 15-EET induces breast cancer cell EMT and cisplatin resistance by up-regulating integrin αvβ3 and activating FAK/PI3K/AKT signaling
por: Luo, Jing, et al.
Publicado: (2018)

Milk Fat Globule-EGF Factor 8 Alleviates Pancreatic Fibrosis by Inhibiting ER Stress-Induced Chaperone-Mediated Autophagy in Mice
por: Ren, Yifan, et al.
Publicado: (2021)

β1 integrin-mediated multicellular resistance in hepatocellular carcinoma through activation of the FAK/Akt pathway
por: Tian, Tao, et al.
Publicado: (2018)

Serum milk fat globule-EGF factor 8 (MFG-E8) as a diagnostic and prognostic biomarker in patients with hepatocellular carcinoma
por: Shimagaki, Tomonari, et al.
Publicado: (2019)

Conformation-dependent binding of a Tetrastatin peptide to α(v)β(3) integrin decreases melanoma progression through FAK/PI(3)K/Akt pathway inhibition
por: Lambert, Eléonore, et al.
Publicado: (2018)

SYST-16 ANXA5 PROMOTES GLIOMA PROGRESSION THROUGH THE FAK/PI3K/AKT PATHWAY
por: Zhang, Xinyuan, et al.
Publicado: (2023)

Cigarette smoke attenuates phagocytic ability of macrophages through down-regulating Milk fat globule-EGF factor 8 (MFG-E8) expressions
por: Wang, Yueqin, et al.
Publicado: (2017)

Regulation of EGF-stimulated activation of the PI-3K/AKT pathway by exocyst-mediated exocytosis
por: An, Seong J., et al.
Publicado: (2022)

The Immunological Role of Milk Fat Globule Membrane
por: Cavaletto, Maria, et al.
Publicado: (2022)

Milk Fat Globule-EGF Factor VIII Attenuates CNS Injury by Promoting Neural Stem Cell Proliferation and Migration after Cerebral Ischemia
por: Cheyuo, Cletus, et al.
Publicado: (2015)

Milk fat globule-EGF factor 8 suppresses the aberrant immune response of systemic lupus erythematosus-derived neutrophils and associated tissue damage
por: Huang, Wei, et al.
Publicado: (2017)

The Healing Effect of Human Milk Fat Globule-EGF Factor 8 Protein (MFG-E8) in A Rat Model of Parkinson’s Disease
por: Nakashima, Yoshiki, et al.
Publicado: (2018)

12N-Substituted Matrinol Derivatives Inhibited the Expression of Fibrogenic Genes via Repressing Integrin/FAK/PI3K/Akt Pathway in Hepatic Stellate Cells
por: Bao, Yunyang, et al.
Publicado: (2019)

Integrin αIIb-Mediated PI3K/Akt Activation in Platelets
por: Niu, Haixia, et al.
Publicado: (2012)

Cinnamaldehyde Suppressed EGF-Induced EMT Process and Inhibits Ovarian Cancer Progression Through PI3K/AKT Pathway
por: Wang, Yue, et al.
Publicado: (2022)

ZKSCAN3 drives tumor metastasis via integrin β4/FAK/AKT mediated epithelial–mesenchymal transition in hepatocellular carcinoma
por: Li, Jieqiong, et al.
Publicado: (2020)

EGF-activated PI3K/Akt signalling coordinates leucine uptake by regulating LAT3 expression in prostate cancer
por: Zhang, Blake K., et al.
Publicado: (2019)

Milk Fat Globule-Epidermal Growth Factor-8 Pretreatment Attenuates Apoptosis and Inflammation via the Integrin-β3 Pathway after Surgical Brain Injury in Rats
por: Xiao, Yicai, et al.
Publicado: (2018)

The anti-tumor NC1 domain of collagen XIX inhibits the FAK/ PI3K/Akt/mTOR signaling pathway through αvβ3 integrin interaction
por: Oudart, Jean-Baptiste, et al.
Publicado: (2015)

Alterations in expression of endometrial milk fat globule-EGF factor 8 (MFG-E8) and leukemia inhibitory factor (LIF) in patients with infertility and endometriosis
por: Schmitz, Carla Regina, et al.
Publicado: (2017)

Galectin-1 induces hepatocellular carcinoma EMT and sorafenib resistance by activating FAK/PI3K/AKT signaling
por: Zhang, P-F, et al.
Publicado: (2016)

Overexpression of HAb18G/CD147 promotes invasion and metastasis via α3β1 integrin mediated FAK-paxillin and FAK-PI3K-Ca(2+) pathways
por: Tang, J., et al.
Publicado: (2008)

Correlation between FAK and EGF-Induced EMT in Colorectal Cancer Cells
por: Huang, Kun, et al.
Publicado: (2020)

The Specificity of EGF-Stimulated IQGAP1 Scaffold Towards the PI3K-Akt Pathway is Defined by the IQ3 motif
por: Chen, Mo, et al.
Publicado: (2019)

Effects of Kindlin-2 on proliferation and migration of VSMC and integrinβ1 andβ3 activity via FAK-PI3K signaling pathway
por: Wu, Xiaolin, et al.
Publicado: (2020)

Deltex-3-like (DTX3L) stimulates metastasis of melanoma through FAK/PI3K/AKT but not MEK/ERK pathway
por: Thang, Nguyen Dinh, et al.
Publicado: (2015)

FNBP1 Facilitates Cervical Cancer Cell Survival by the Constitutive Activation of FAK/PI3K/AKT/mTOR Signaling
por: Zhang, Jun, et al.
Publicado: (2023)

Hydrostatic Compress Force Enhances the Viability and Decreases the Apoptosis of Condylar Chondrocytes through Integrin-FAK-ERK/PI3K Pathway
por: Ma, Dandan, et al.
Publicado: (2016)

Laminin promotes differentiation of rat embryonic stem cells into cardiomyocytes by activating the integrin/FAK/PI3K p85 pathway
por: Wang, Duo, et al.
Publicado: (2019)

Benefits of Lactoferrin, Osteopontin and Milk Fat Globule Membranes for Infants
por: Demmelmair, Hans, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_e84dr1kauufbcqqdsa8rnmbeqv