Cargando…

ARD1 contributes to IKKβ-mediated breast cancer tumorigenesis

The expression of IκB kinase β (IKKβ) promotes the growth of breast cancer cells. Meanwhile, IKKβ mediates the phosphorylation and subsequent degradation of arrest-defective protein 1 (ARD1). However, the relationship between IKKβ and ARD1 in the occurrence of breast cancer has not been reported. In...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yu, Zhou, Hang, Tao, Yongjun, Liu, Xingyu, Yuan, Zhu, Nie, Chunlai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113314/ https://www.ncbi.nlm.nih.gov/pubmed/30154412 http://dx.doi.org/10.1038/s41419-018-0921-2

Ejemplares similares

IKKβ acts as a tumor suppressor in cancer-associated fibroblasts during intestinal tumorigenesis
por: Pallangyo, Charles K., et al.
Publicado: (2015)

IKK inhibition by BMS-345541 suppresses breast tumorigenesis and metastases by targeting GD2(+) cancer stem cells
por: Battula, Venkata Lokesh, et al.
Publicado: (2017)

Targeting IKKβ in Cancer: Challenges and Opportunities for the Therapeutic Utilisation of IKKβ Inhibitors
por: Prescott, Jack A., et al.
Publicado: (2018)

An unexpected twist to the activation of IKKβ: TAK1 primes IKKβ for activation by autophosphorylation
por: Zhang, Jiazhen, et al.
Publicado: (2014)

Hit identification of IKKβ natural product inhibitor
por: Leung, Chung-Hang, et al.
Publicado: (2013)

IKKα and IKKβ Regulation of DNA Damage-Induced Cleavage of Huntingtin
por: Khoshnan, Ali, et al.
Publicado: (2009)

Regulation of breast cancer induced bone disease by cancer-specific IKKβ
por: Marino, Silvia, et al.
Publicado: (2018)

Coordination of the canonical and noncanonical IKK/NF-κB signaling pathways in HTLV-I Tax-mediated tumorigenesis
por: Fu, Jing, et al.
Publicado: (2011)

IKKβ inhibitor in combination with bortezomib induces cytotoxicity in breast cancer cells
por: HIDESHIMA, HIROMASA, et al.
Publicado: (2014)

Pharmacological Inhibition of the Skeletal IKKβ Reduces Breast Cancer-Induced Osteolysis
por: Marino, Silvia, et al.
Publicado: (2018)

Context-Dependent Role of IKKβ in Cancer
por: Page, Angustias, et al.
Publicado: (2017)

IKKβ links vascular inflammation to obesity and atherosclerosis
por: Sui, Yipeng, et al.
Publicado: (2014)

IκB kinase (IKK)β, but not IKKα, is a critical mediator of osteoclast survival and is required for inflammation-induced bone loss
por: Ruocco, Maria Grazia, et al.
Publicado: (2005)

Anti-inflammatory therapy of atherosclerosis: focusing on IKKβ
por: Gan, Jiali, et al.
Publicado: (2023)

Recent Advances in Understanding the Role of IKKβ in Cardiometabolic Diseases
por: Hernandez, Rebecca, et al.
Publicado: (2021)

Substrate-specific recognition of IKKs mediated by USP16 facilitates autoimmune inflammation
por: Yu, Jian-shuai, et al.
Publicado: (2021)

Crystal structure of inhibitor of κB kinase β (IKKβ)
por: Xu, Guozhou, et al.
Publicado: (2011)

Selective autophagic degradation of the IKK complex in Drosophila is mediated by Kenny/IKKγ to control inflammation
por: Jacomin, Anne-Claire, et al.
Publicado: (2019)

MAP4K3/GLK inhibits Treg differentiation by direct phosphorylating IKKβ and inducing IKKβ-mediated FoxO1 nuclear export and Foxp3 downregulation
por: Chi, Jyun-Ni, et al.
Publicado: (2022)

IKKβ Is Essential for Adipocyte Survival and Adaptive Adipose Remodeling in Obesity
por: Park, Se-Hyung, et al.
Publicado: (2016)

Mapping the IκB Kinase β (IKKβ)-binding Interface of the B14 Protein, a Vaccinia Virus Inhibitor of IKKβ-mediated Activation of Nuclear Factor κB
por: Benfield, Camilla T. O., et al.
Publicado: (2011)

Non-canonical Notch signaling activates IL-6/JAK/STAT signaling in breast tumor cells and is controlled by p53 and IKKα/IKKβ
por: Jin, S, et al.
Publicado: (2013)

IKKβ/NF-κB and the miscreant macrophage
por: Timmer, Anjuli M., et al.
Publicado: (2008)

IKKβ is required for the formation of the NLRP3 inflammasome
por: Nanda, Sambit K, et al.
Publicado: (2021)

Roles for the IKK-Related Kinases TBK1 and IKKε in Cancer
por: Durand, Joel K., et al.
Publicado: (2018)

IKKα and IKKβ Each Function to Regulate NF-κB Activation in the TNF-Induced/Canonical Pathway
por: Adli, Mazhar, et al.
Publicado: (2010)

Inflammatory related gene IKKα, IKKβ, IKKγ cooperates to determine liver cancer stem cells progression by altering telomere via heterochromatin protein 1-HOTAIR axis
por: An, Jiahui, et al.
Publicado: (2016)

Salmonella Effector SpvB Inhibits NF-κB Activity via KEAP1-Mediated Downregulation of IKKβ
por: Yang, Sidi, et al.
Publicado: (2021)

Inhibition of IKK-β by epidioxysterols from the flowers of Calotropis gigantea (Niu jiao gua)
por: Parhira, Supawadee, et al.
Publicado: (2016)

Mechanism of PP2A-mediated IKKβ dephosphorylation: a systems biological approach
por: Witt, Johannes, et al.
Publicado: (2009)

IKKβ signaling mediates metabolic changes in the hypothalamus of a Huntington disease mouse model
por: Soylu-Kucharz, Rana, et al.
Publicado: (2022)

The IKKβ Subunit of IκB Kinase (IKK) is Essential for Nuclear Factor κB Activation and Prevention of Apoptosis
por: Li, Zhi-Wei, et al.
Publicado: (1999)

A Novel Homozygous Mutation Destabilizes IKKβ and Leads to Human Combined Immunodeficiency
por: Qin, Tao, et al.
Publicado: (2021)

Akt+ IKKα/β+ Rab5+ Signalosome Mediate the Endosomal Recruitment of Sec61 and Contribute to Cross-Presentation in Bone Marrow Precursor Cells
por: Xu, Dan Dan, et al.
Publicado: (2020)

The MGF300-2R protein of African swine fever virus is associated with viral pathogenicity by promoting the autophagic degradation of IKKα and IKKβ through the recruitment of TOLLIP
por: Wang, Tao, et al.
Publicado: (2023)

Curcumin suppresses tumorigenesis by ferroptosis in breast cancer
por: Cao, Xuelei, et al.
Publicado: (2022)

The Role of IKKβ in Venezuelan Equine Encephalitis Virus Infection
por: Amaya, Moushimi, et al.
Publicado: (2014)

IKK-mediated CYLD phosphorylation and cellular redox activity
por: Erol, Adnan
Publicado: (2022)

IKKα contributes to UVB-induced VEGF expression by regulating AP-1 transactivation
por: Dong, Wen, et al.
Publicado: (2012)

IKKβ Regulates the Repair of DNA Double-Strand Breaks Induced by Ionizing Radiation in MCF-7 Breast Cancer Cells
por: Wu, Lixian, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_3g82uu025mhli4ipseqmu5ktnf