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Metabolic reprogramming of acute lymphoblastic leukemia cells in response to glucocorticoid treatment

Glucocorticoids (GCs) are metabolic hormones with immunosuppressive effects that have proven effective drugs against childhood acute lymphoblastic leukemia (ALL). Yet, the role of metabolic reprogramming in GC-induced ALL cell death is poorly understood. GCs efficiently block glucose uptake and meta...

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Detalles Bibliográficos
Autores principales:	Dyczynski, Matheus, Vesterlund, Mattias, Björklund, Ann-Charlotte, Zachariadis, Vasilios, Janssen, Jerry, Gallart-Ayala, Hector, Daskalaki, Evangelia, Wheelock, Craig E., Lehtiö, Janne, Grandér, Dan, Tamm, Katja Pokrovskaja, Nilsson, Roland
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113325/ https://www.ncbi.nlm.nih.gov/pubmed/30154400 http://dx.doi.org/10.1038/s41419-018-0625-7

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