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Nuclear YAP localization as a key regulator of podocyte function

Podocytes are crucial for the establishment of the blood-urine filtration barrier in the glomeruli of the kidney. These cells are mainly affected during glomerulopathies causing proteinuria and kidney function impairment. Ongoing podocyte injury leads to podocyte loss, finally followed by end-stage...

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Detalles Bibliográficos
Autores principales: Bonse, Jakob, Wennmann, Dirk Oliver, Kremerskothen, Joachim, Weide, Thomas, Michgehl, Ulf, Pavenstädt, Hermann, Vollenbröker, Beate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113334/
https://www.ncbi.nlm.nih.gov/pubmed/30154411
http://dx.doi.org/10.1038/s41419-018-0878-1