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Human Campylobacteriosis in Italy: Emergence of Multi-Drug Resistance to Ciprofloxacin, Tetracycline, and Erythromycin

Campylobacter spp. is one of the main cause of bacterial gastroenteritis in the world. The increase of antibiotic resistance in this species is a threat to public health. A Campylobacter spp. surveillance study was performed in Italy in the 2013–2016 period by the Enter-Net Italia network. The most...

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Autores principales: García-Fernández, Aurora, Dionisi, Anna M., Arena, Sergio, Iglesias-Torrens, Yaidelys, Carattoli, Alessandra, Luzzi, Ida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113387/
https://www.ncbi.nlm.nih.gov/pubmed/30186251
http://dx.doi.org/10.3389/fmicb.2018.01906
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author García-Fernández, Aurora
Dionisi, Anna M.
Arena, Sergio
Iglesias-Torrens, Yaidelys
Carattoli, Alessandra
Luzzi, Ida
author_facet García-Fernández, Aurora
Dionisi, Anna M.
Arena, Sergio
Iglesias-Torrens, Yaidelys
Carattoli, Alessandra
Luzzi, Ida
author_sort García-Fernández, Aurora
collection PubMed
description Campylobacter spp. is one of the main cause of bacterial gastroenteritis in the world. The increase of antibiotic resistance in this species is a threat to public health. A Campylobacter spp. surveillance study was performed in Italy in the 2013–2016 period by the Enter-Net Italia network. The most prevalent Campylobacter species identified causing gastroenteritis was Campylobacter jejuni (73.4%) and 45% of all the annual cases of campylobacteriosis were reported in the summer period. High rates of ciprofloxacin and tetracycline resistance in Campylobacter spp. have been observed. An increasing percentage of Campylobacter coli strains simultaneously resistant to ciprofloxacin, tetracycline and erythromycin has been found. Molecular mechanisms of resistance have been investigated and the role of efflux pumps evaluated. Antibiotic resistance in Campylobacter spp. is an increasing serious threat that requires coordinated action to minimize the emergence and spread of antimicrobial resistant strains from animals to humans throughout the food chain.
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spelling pubmed-61133872018-09-05 Human Campylobacteriosis in Italy: Emergence of Multi-Drug Resistance to Ciprofloxacin, Tetracycline, and Erythromycin García-Fernández, Aurora Dionisi, Anna M. Arena, Sergio Iglesias-Torrens, Yaidelys Carattoli, Alessandra Luzzi, Ida Front Microbiol Microbiology Campylobacter spp. is one of the main cause of bacterial gastroenteritis in the world. The increase of antibiotic resistance in this species is a threat to public health. A Campylobacter spp. surveillance study was performed in Italy in the 2013–2016 period by the Enter-Net Italia network. The most prevalent Campylobacter species identified causing gastroenteritis was Campylobacter jejuni (73.4%) and 45% of all the annual cases of campylobacteriosis were reported in the summer period. High rates of ciprofloxacin and tetracycline resistance in Campylobacter spp. have been observed. An increasing percentage of Campylobacter coli strains simultaneously resistant to ciprofloxacin, tetracycline and erythromycin has been found. Molecular mechanisms of resistance have been investigated and the role of efflux pumps evaluated. Antibiotic resistance in Campylobacter spp. is an increasing serious threat that requires coordinated action to minimize the emergence and spread of antimicrobial resistant strains from animals to humans throughout the food chain. Frontiers Media S.A. 2018-08-22 /pmc/articles/PMC6113387/ /pubmed/30186251 http://dx.doi.org/10.3389/fmicb.2018.01906 Text en Copyright © 2018 García-Fernández, Dionisi, Arena, Iglesias-Torrens, Carattoli and Luzzi. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Microbiology
García-Fernández, Aurora
Dionisi, Anna M.
Arena, Sergio
Iglesias-Torrens, Yaidelys
Carattoli, Alessandra
Luzzi, Ida
Human Campylobacteriosis in Italy: Emergence of Multi-Drug Resistance to Ciprofloxacin, Tetracycline, and Erythromycin
title Human Campylobacteriosis in Italy: Emergence of Multi-Drug Resistance to Ciprofloxacin, Tetracycline, and Erythromycin
title_full Human Campylobacteriosis in Italy: Emergence of Multi-Drug Resistance to Ciprofloxacin, Tetracycline, and Erythromycin
title_fullStr Human Campylobacteriosis in Italy: Emergence of Multi-Drug Resistance to Ciprofloxacin, Tetracycline, and Erythromycin
title_full_unstemmed Human Campylobacteriosis in Italy: Emergence of Multi-Drug Resistance to Ciprofloxacin, Tetracycline, and Erythromycin
title_short Human Campylobacteriosis in Italy: Emergence of Multi-Drug Resistance to Ciprofloxacin, Tetracycline, and Erythromycin
title_sort human campylobacteriosis in italy: emergence of multi-drug resistance to ciprofloxacin, tetracycline, and erythromycin
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113387/
https://www.ncbi.nlm.nih.gov/pubmed/30186251
http://dx.doi.org/10.3389/fmicb.2018.01906
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