Repositioning of the β-Blocker Carvedilol as a Novel Autophagy Inducer That Inhibits the NLRP3 Inflammasome

The NLRP3 inflammasome is a multiprotein complex that plays a key role in the innate immune system, and aberrant activation of this complex is involved in the pathogenesis of inflammatory diseases. Carvedilol (CVL) is an α-, β-blocker used to treat high blood pressure and congestive heart failure; h...

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Detalles Bibliográficos
Autores principales: Wong, Wei-Ting, Li, Lan-Hui, Rao, Yerra Koteswara, Yang, Shih-Ping, Cheng, Shu-Meng, Lin, Wen-Yu, Cheng, Cheng-Chung, Chen, Ann, Hua, Kuo-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113403/
https://www.ncbi.nlm.nih.gov/pubmed/30186288
http://dx.doi.org/10.3389/fimmu.2018.01920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113403/
https://www.ncbi.nlm.nih.gov/pubmed/30186288
http://dx.doi.org/10.3389/fimmu.2018.01920

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