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Phase II trial of biweekly cetuximab and irinotecan as third‐line therapy for pretreated KRAS exon 2 wild‐type colorectal cancer
Efficacy and safety of biweekly cetuximab plus irinotecan were evaluated to provide guidance for its use in Japan as third‐line treatment for pretreated metastatic colorectal cancer (mCRC) patients harboring wild‐type KRAS exon 2. Objective response rate (ORR) was used as primary endpoint based on a...
Autores principales: | Osumi, Hiroki, Shinozaki, Eiji, Mashima, Tetsuo, Wakatsuki, Takeru, Suenaga, Mitsukuni, Ichimura, Takashi, Ogura, Mariko, Ota, Yumiko, Nakayama, Izuma, Takahari, Daisuke, Chin, Keisho, Miki, Yoshio, Yamaguchi, Kensei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113428/ https://www.ncbi.nlm.nih.gov/pubmed/29908105 http://dx.doi.org/10.1111/cas.13698 |
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