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ASP8273 tolerability and antitumor activity in tyrosine kinase inhibitor‐naïve Japanese patients with EGFR mutation‐positive non‐small‐cell lung cancer
Epidermal growth factor receptor (EGFR) activating mutations occur in approximately 50% of East Asian patients with non‐small‐cell lung cancer (NSCLC) and confer sensitivity to tyrosine kinase inhibitors (TKIs). ASP8273 is an irreversible EGFR‐TKI, given orally, that inhibits EGFR activating mutatio...
Autores principales: | Azuma, Koichi, Nishio, Makoto, Hayashi, Hidetoshi, Kiura, Katsuyuki, Satouchi, Miyako, Sugawara, Shunichi, Hida, Toyoaki, Iwamoto, Yasuo, Inoue, Akira, Takeda, Koji, Ikeda, Satoshi, Nakagawa, Tomoki, Takeda, Kentaro, Asahina, Seitaro, Komatsu, Kanji, Morita, Satoshi, Fukuoka, Masahiro, Nakagawa, Kazuhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113441/ https://www.ncbi.nlm.nih.gov/pubmed/29807396 http://dx.doi.org/10.1111/cas.13651 |
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