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ASP8273 tolerability and antitumor activity in tyrosine kinase inhibitor‐naïve Japanese patients with EGFR mutation‐positive non‐small‐cell lung cancer

Epidermal growth factor receptor (EGFR) activating mutations occur in approximately 50% of East Asian patients with non‐small‐cell lung cancer (NSCLC) and confer sensitivity to tyrosine kinase inhibitors (TKIs). ASP8273 is an irreversible EGFR‐TKI, given orally, that inhibits EGFR activating mutatio...

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Detalles Bibliográficos
Autores principales: Azuma, Koichi, Nishio, Makoto, Hayashi, Hidetoshi, Kiura, Katsuyuki, Satouchi, Miyako, Sugawara, Shunichi, Hida, Toyoaki, Iwamoto, Yasuo, Inoue, Akira, Takeda, Koji, Ikeda, Satoshi, Nakagawa, Tomoki, Takeda, Kentaro, Asahina, Seitaro, Komatsu, Kanji, Morita, Satoshi, Fukuoka, Masahiro, Nakagawa, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113441/
https://www.ncbi.nlm.nih.gov/pubmed/29807396
http://dx.doi.org/10.1111/cas.13651

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