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DEAD box protein DDX1 promotes colorectal tumorigenesis through transcriptional activation of the LGR5 gene

DDX1, a member of the DEAD box RNA helicase family, plays a critical role in testicular tumors. However, it remains to be clarified whether DDX1 is involved in other types of malignant tumors such as colorectal cancer. We disrupted the DDX1 gene in a human colorectal cancer cell line LoVo using the...

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Detalles Bibliográficos
Autores principales:	Tanaka, Kiyoko, Ikeda, Narumi, Miyashita, Kazuya, Nuriya, Hideko, Hara, Takahiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113447/ https://www.ncbi.nlm.nih.gov/pubmed/29869821 http://dx.doi.org/10.1111/cas.13661

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