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PIK3CA mutation profiling in patients with breast cancer, using a highly sensitive detection system

PIK3CA mutations are common activating mutations associated with breast cancer (occurring in 20–30% of all cases) and are potent predictive markers for responses to PI3K inhibitors. Thus, it is important to develop sensitive methods to detect these mutations. We established a novel detection method...

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Detalles Bibliográficos
Autores principales:	Shimoi, Tatsunori, Hamada, Akinobu, Yamagishi, Marifu, Hirai, Mitsuharu, Yoshida, Masayuki, Nishikawa, Tadaaki, Sudo, Kazuki, Shimomura, Akihiko, Noguchi, Emi, Yunokawa, Mayu, Yonemori, Kan, Shimizu, Chikako, Kinoshita, Takayuki, Fukuda, Takahiro, Fujiwara, Yasuhiro, Tamura, Kenji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113507/ https://www.ncbi.nlm.nih.gov/pubmed/29906308 http://dx.doi.org/10.1111/cas.13696

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