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NADPH Oxidase and Guanylate Binding Protein 5 Restrict Survival of Avirulent Type III Strains of Toxoplasma gondii in Naive Macrophages

Phagocytic cells are the first line of innate defense against intracellular pathogens, and yet Toxoplasma gondii is renowned for its ability to survive in macrophages, although this paradigm is based on virulent type I parasites. Surprisingly, we find that avirulent type III parasites are preferenti...

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Detalles Bibliográficos
Autores principales:	Matta, Sumit K., Patten, Kelley, Wang, Quiling, Kim, Bae-Hoon, MacMicking, John D., Sibley, L. David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113620/ https://www.ncbi.nlm.nih.gov/pubmed/30154263 http://dx.doi.org/10.1128/mBio.01393-18

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