Aminopeptidase N (CD13): Expression, Prognostic Impact, and Use as Therapeutic Target for Tissue Factor Induced Tumor Vascular Infarction in Soft Tissue Sarcoma

Aminopeptidase N (CD13) is expressed on tumor vasculature and tumor cells. It represents a candidate for targeted therapy, e.g., by truncated tissue factor (tTF)-NGR, binding to CD13, and causing tumor vascular thrombosis. We analyzed CD13 expression by immunohistochemistry in 97 patients with STS w...

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Detalles Bibliográficos
Autores principales: Kessler, Torsten, Baumeier, Ariane, Brand, Caroline, Grau, Michael, Angenendt, Linus, Harrach, Saliha, Stalmann, Ursula, Schmidt, Lars Henning, Gosheger, Georg, Hardes, Jendrik, Andreou, Dimosthenis, Dreischalück, Johannes, Lenz, Georg, Wardelmann, Eva, Mesters, Rolf M., Schwöppe, Christian, Berdel, Wolfgang E., Hartmann, Wolfgang, Schliemann, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113655/
https://www.ncbi.nlm.nih.gov/pubmed/30125801
http://dx.doi.org/10.1016/j.tranon.2018.08.004

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