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DNA repair pathways and cisplatin resistance: an intimate relationship

The main goal of chemotherapeutic drugs is to induce massive cell death in tumors. Cisplatin is an antitumor drug widely used to treat several types of cancer. Despite its remarkable efficiency, most tumors show intrinsic or acquired drug resistance. The primary biological target of cisplatin is gen...

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Detalles Bibliográficos
Autores principales:	Rocha, Clarissa Ribeiro Reily, Silva, Matheus Molina, Quinet, Annabel, Cabral-Neto, Januario Bispo, Menck, Carlos Frederico Martins
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2018
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113849/ https://www.ncbi.nlm.nih.gov/pubmed/30208165 http://dx.doi.org/10.6061/clinics/2018/e478s

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