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Effective control of neuropathic pain by transient expression of hepatocyte growth factor in a mouse chronic constriction injury model

Hepatocyte growth factor (HGF) is a multifunctional protein that contains angiogenic and neurotrophic properties. In the current study, we investigated the analgesic effects of HGF by using a plasmid DNA that was designed to express 2 isoforms of human HGF—pCK-HGF-X7 (or VM202)—in a chronic constric...

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Detalles Bibliográficos
Autores principales: Nho, Boram, Lee, Junghun, Lee, Junsub, Ko, Kyeong Ryang, Lee, Sung Joong, Kim, Sunyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113864/
https://www.ncbi.nlm.nih.gov/pubmed/29913557
http://dx.doi.org/10.1096/fj.201800476R