Cargando…

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1

Epigenetic factors (EFs) regulate multiple aspects of cerebral cortex development, including proliferation, differentiation, laminar fate, and regional identity. The same neurodevelopmental processes are also regulated by transcription factors (TFs), notably the Pax6→ Tbr2→ Tbr1 cascade expressed se...

Descripción completa

Detalles Bibliográficos
Autores principales:	Elsen, Gina E., Bedogni, Francesco, Hodge, Rebecca D., Bammler, Theo K., MacDonald, James W., Lindtner, Susan, Rubenstein, John L. R., Hevner, Robert F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113890/ https://www.ncbi.nlm.nih.gov/pubmed/30186101 http://dx.doi.org/10.3389/fnins.2018.00571

Ejemplares similares

TBR1 regulates autism risk genes in the developing neocortex
por: Notwell, James H., et al.
Publicado: (2016)

Unipolar (Dendritic) Brush Cells Are Morphologically Complex and Require Tbr2 for Differentiation and Migration
por: McDonough, Ashley, et al.
Publicado: (2021)

Progressive loss of PAX6, TBR2, NEUROD and TBR1 mRNA gradients correlates with translocation of EMX2 to the cortical plate during human cortical development
por: Bayatti, Nadhim, et al.
Publicado: (2008)

The exopolyphosphatase TbrPPX1 of Trypanosoma brucei
por: Luginbuehl, Edith, et al.
Publicado: (2011)

Tbr1 instructs laminar patterning of retinal ganglion cell dendrites
por: Liu, Jinyue, et al.
Publicado: (2018)

Gene Conversion Transfers the GAF-A Domain of Phosphodiesterase TbrPDEB1 to One Allele of TbrPDEB2 of Trypanosoma brucei
por: Kunz, Stefan, et al.
Publicado: (2009)

ANTIPYRETIC ACTIVITY OF TBR-002, A HERBAL FORMULATION
por: Subramaniam, A., et al.
Publicado: (1995)

Functional characterization of TBR1 variants in neurodevelopmental disorder
por: den Hoed, Joery, et al.
Publicado: (2018)

Complete Genome Sequence of Luteitalea sp. Strain TBR-22
por: Yamamoto, Kyosuke, et al.
Publicado: (2022)

Tbr1 Misexpression Alters Neuronal Development in the Cerebral Cortex
por: Crespo, Inmaculada, et al.
Publicado: (2022)

BepiTBR: T-B reciprocity enhances B cell epitope prediction
por: Zhu, James, et al.
Publicado: (2022)

Enhancing WNT Signaling Restores Cortical Neuronal Spine Maturation and Synaptogenesis in Tbr1 Mutants
por: Darbandi, Siavash Fazel, et al.
Publicado: (2020)

LiCl treatment leads to long-term restoration of spine maturation and synaptogenesis in adult Tbr1 mutants
por: Fazel Darbandi, Siavash, et al.
Publicado: (2022)

Cortical and Clonal Contribution of Tbr2 Expressing Progenitors in the Developing Mouse Brain
por: Vasistha, Navneet A., et al.
Publicado: (2015)

A TBR1-K228E Mutation Induces Tbr1 Upregulation, Altered Cortical Distribution of Interneurons, Increased Inhibitory Synaptic Transmission, and Autistic-Like Behavioral Deficits in Mice
por: Yook, Chaehyun, et al.
Publicado: (2019)

Screening the Pathogen Box to Discover and Characterize New Cruzain and TbrCatL Inhibitors
por: do Valle Moreira, Thales, et al.
Publicado: (2023)

The evolutionarily conserved function of TBR1 in controlling the size of anterior commissure in human and mouse brains
por: Hsueh, Yi-Ping, et al.
Publicado: (2020)

Adult Expression of Tbr2 Is Required for the Maintenance but Not Survival of Intrinsically Photosensitive Retinal Ganglion Cells
por: Abed, Sadaf, et al.
Publicado: (2022)

Characterization of the TBR1 interactome: variants associated with neurodevelopmental disorders disrupt novel protein interactions
por: Sollis, Elliot, et al.
Publicado: (2022)

Prenatal β-catenin/Brn2/Tbr2 transcriptional cascade regulates adult social and stereotypic behaviors
por: Belinson, H, et al.
Publicado: (2016)

TBR2 coordinates neurogenesis expansion and precise microcircuit organization via Protocadherin 19 in the mammalian cortex
por: Lv, Xiaohui, et al.
Publicado: (2019)

TBR-760, a Dopamine-Somatostatin Compound, Arrests Growth of Aggressive Nonfunctioning Pituitary Adenomas in Mice
por: Halem, Heather A, et al.
Publicado: (2020)

A de novo frameshift pathogenic variant in TBR1 identified in autism without intellectual disability
por: Sapey-Triomphe, Laurie-Anne, et al.
Publicado: (2020)

Haploinsufficiency of autism causative gene Tbr1 impairs olfactory discrimination and neuronal activation of the olfactory system in mice
por: Huang, Tzyy-Nan, et al.
Publicado: (2019)

Discovery of Diaryl Ether Substituted Tetrahydrophthalazinones as TbrPDEB1 Inhibitors Following Structure-Based Virtual Screening
por: de Heuvel, Erik, et al.
Publicado: (2021)

Exploring the Activity Profile of TbrPDEB1 and hPDE4 Inhibitors Using Free Energy Perturbation
por: Zara, Lorena, et al.
Publicado: (2022)

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
por: Bedogni, Francesco, et al.
Publicado: (2021)

Hyper-Pseudo-Viscoelastic Model and Parameter Identification for Describing Tensile Recovery Stress–Strain Responses of Rubber Components in TBR
por: Pan, Gao, et al.
Publicado: (2022)

Dietary zinc supplementation rescues fear-based learning and synaptic function in the Tbr1(+/−) mouse model of autism spectrum disorders
por: Lee, Kevin, et al.
Publicado: (2022)

TBR2-immunopsitive unipolar brush cells are associated with ectopic zebrin II-immunoreactive Purkinje cell clusters in the cerebellum of scrambler mice
por: Chung, Seung-Hyuk, et al.
Publicado: (2010)

OR06-02 TBR-760, a Chimeric Somatostatin-Dopamine Compound, Arrests Aggressive Non-Functioning Pituitary Adenoma Growth In Vivo
por: Halem, Heather A, et al.
Publicado: (2020)

Mid-pregnancy maternal immune activation increases Pax6-positive and Tbr2-positive neural progenitor cells and causes integrated stress response in the fetal brain in a mouse model of maternal viral infection
por: Tsukada, Tsuyoshi, et al.
Publicado: (2021)

Neuronal excitation upregulates Tbr1, a high-confidence risk gene of autism, mediating Grin2b expression in the adult brain
por: Chuang, Hsiu-Chun, et al.
Publicado: (2014)

N-acetylcysteine attenuates lipopolysaccharide-induced impairment in lamination of Ctip2-and Tbr1- expressing cortical neurons in the developing rat fetal brain
por: Chao, Ming-Wei, et al.
Publicado: (2016)

Single nucleotide polymorphisms and copy-number variations in the Trypanosoma brucei repeat (TBR) sequence can be used to enhance amplification and genotyping of Trypanozoon strains
por: Van Reet, Nick, et al.
Publicado: (2021)

Targeting a Subpocket in Trypanosoma brucei Phosphodiesterase B1 (TbrPDEB1) Enables the Structure-Based Discovery of Selective Inhibitors with Trypanocidal Activity
por: Blaazer, Antoni R., et al.
Publicado: (2018)

Quail-chick grafting experiments corroborate that Tbr1-positive eminential prethalamic neurons migrate along three streams into hypothalamus, subpallium and septocommissural areas
por: Alonso, Antonia, et al.
Publicado: (2021)

Improved bacterial leaf blight disease resistance in the major elite Vietnamese rice cultivar TBR225 via editing of the OsSWEET14 promoter
por: Duy, Phuong Nguyen, et al.
Publicado: (2021)

Perinatal IL-1β-induced inflammation suppresses Tbr2(+) intermediate progenitor cell proliferation in the developing hippocampus accompanied by long-term behavioral deficits
por: Veerasammy, Stephanie, et al.
Publicado: (2020)

Comparison of ITS-1 and TBR-1/2 primer sensitivity for the detection of Trypanosoma evansi local isolates in experimental rats using a polymerase chain reaction
por: Suprihati, Endang, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ljkr2e4u8jhapoce4j6ibag2h5