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Beta-cell hubs maintain Ca(2+) oscillations in human and mouse islet simulations
Islet β-cells are responsible for secreting all circulating insulin in response to rising plasma glucose concentrations. These cells are a phenotypically diverse population that express great functional heterogeneity. In mice, certain β-cells (termed ‘hubs’) have been shown to be crucial for dictati...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113907/ https://www.ncbi.nlm.nih.gov/pubmed/30142036 http://dx.doi.org/10.1080/19382014.2018.1493316 |