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Inflammasome-Independent NALP3 Contributes to High-Salt Induced Endothelial Dysfunction

Backgrounds and Aims: Na(+) is an important nutrient and its intake, mainly from salt (NaCl), is essential for normal physiological function. However, high salt intake may lead to vascular injury, independent of a rise in blood pressure (BP). Canonical NALP3 inflammasome activation is a caspase-1 me...

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Detalles Bibliográficos
Autores principales: Fu, Hui, Chen, Ji-Kuai, Lu, Wen-Jie, Jiang, Yu-Jie, Wang, Yuan-Yuan, Li, Dong-Jie, Shen, Fu-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113916/
https://www.ncbi.nlm.nih.gov/pubmed/30186184
http://dx.doi.org/10.3389/fphar.2018.00968

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