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Inflammasome-Independent NALP3 Contributes to High-Salt Induced Endothelial Dysfunction
Backgrounds and Aims: Na(+) is an important nutrient and its intake, mainly from salt (NaCl), is essential for normal physiological function. However, high salt intake may lead to vascular injury, independent of a rise in blood pressure (BP). Canonical NALP3 inflammasome activation is a caspase-1 me...
Autores principales: | Fu, Hui, Chen, Ji-Kuai, Lu, Wen-Jie, Jiang, Yu-Jie, Wang, Yuan-Yuan, Li, Dong-Jie, Shen, Fu-Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113916/ https://www.ncbi.nlm.nih.gov/pubmed/30186184 http://dx.doi.org/10.3389/fphar.2018.00968 |
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