Safety and efficacy of the bumped kinase inhibitor BKI-1553 in pregnant sheep experimentally infected with Neospora caninum tachyzoites

Neospora caninum is one of the main causes of abortion in cattle, and recent studies have highlighted its relevance as an abortifacient in small ruminants. Vaccines or drugs for the control of neosporosis are lacking. Bumped kinase inhibitors (BKIs), which are ATP-competitive inhibitors of calcium d...

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Detalles Bibliográficos
Autores principales: Sánchez-Sánchez, Roberto, Ferre, Ignacio, Re, Michela, Vázquez, Patricia, Ferrer, Luis Miguel, Blanco-Murcia, Javier, Regidor-Cerrillo, Javier, Pizarro Díaz, Manuel, González-Huecas, Marta, Tabanera, Enrique, García-Lunar, Paula, Benavides, Julio, Castaño, Pablo, Hemphill, Andrew, Hulverson, Matthew A., Whitman, Grant R., Rivas, Kasey L., Choi, Ryan, Ojo, Kayode K., Barrett, Lynn K., Van Voorhis, Wesley C., Ortega-Mora, Luis Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114101/
https://www.ncbi.nlm.nih.gov/pubmed/29501973
http://dx.doi.org/10.1016/j.ijpddr.2018.02.003

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