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In vitro and in vivo pharmacodynamics of three novel antileishmanial lead series

OBJECTIVES: Three new chemical series (bicyclic nitroimidazoles, aminopyrazoles and oxaboroles) were selected by Drugs for Neglected Diseases initiative as potential new drug leads for leishmaniasis. Pharmacodynamics studies included both in vitro and in vivo efficacy, cross-resistance profiling aga...

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Detalles Bibliográficos
Autores principales:	Van den Kerkhof, M., Mabille, D., Chatelain, E., Mowbray, C.E., Braillard, S., Hendrickx, S., Maes, L., Caljon, G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114106/ https://www.ncbi.nlm.nih.gov/pubmed/29425734 http://dx.doi.org/10.1016/j.ijpddr.2018.01.006

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